Home Current issue Ahead of print Search About us Editorial board Archives Submit article Instructions Subscribe Contacts Login 
  • Users Online: 274
  • Home
  • Print this page
  • Email this page
Year : 2022  |  Volume : 14  |  Issue : 2  |  Page : 99-103

Ultra fast papanicolaou stain versus conventional papanicolaou stain in oral cytology smears: A comparative study

1 Department of Oral Pathology, Government Dental College and Hospital, Hyderabad, Telangana, India
2 Department of Oral Pathology and Microbiology, Government Dental College and Hospital, Hyderabad, Telangana, India

Correspondence Address:
Paremala Konda
Room No: 331, Department of Oral Pathology, Government Dental College and Hospital, Afzalgunj, Hyderabad - 500 012, Telangana
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jorr.jorr_70_21

Rights and Permissions

Background: Exfoliative cytology is the technique of microscopic examination of shed or desquamated cells from the epithelial surface of mucous membrane. Papanicolaou stain (PAP) is the common stain used for these cytological smears. Conventional PAP (cPAP) stain has undergone many modifications, of these ultrafast PAP (UFPAP) is a popular stain used as it shortens the staining time and quality. UFPAP was discovered as a fusion of Romanowsky and PAP. Aim and Objectives: To evaluate and estimate the quality of UFPAP and c PAP stains in oral cytology smears of normal mucosa (NM), oral squamous cell carcinoma (OSCC), and oral potentially malignant disorders (OPMDs). Materials and Methods: 50 samples/smears were collected from outpatients from the Government Dental College and Hospital, Hyderabad. Samples include 10 cases of NM, 20 cases each of OPMDs (leukoplakia) and OSCC. Two cytological smears of representative areas were obtained and each smear is stained by the cPAP and UFPAP stains, respectively. Results and Observation: The quality index is obtained for the comparison of UFPAP and cPAP stains by using four parameters like - nuclear details, over all staining, background staining, and cell morphology. QI for all parameters of UFPAP staining was good compared to cPAP and percentage of UFPAP for NM, OPMDs and OSCC was 92.7%, 88.1%, 66.3% respectively. Conclusion: The study concludes that UFPAP staining is used for diagnosis in a regular oral cytology smears to offer immediate diagnosis of OPMDs and OSCCs.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded155    
    Comments [Add]    

Recommend this journal